Delivery Method: Both treatments support cellular health by boosting NAD+ levels, but they differ in how they do it. NAD+ treatments deliver NAD+ directly into the bloodstream, while Niagen NR (nicotinamide riboside) is a precursor—your body converts it into NAD+ after it's administered.

Treatment Experience: NAD+ IV treatments can sometimes be intense, especially at higher doses. They may cause discomfort during infusion, such as chest tightness, flushing, or nausea. In contrast, Niagen NR treatments—whether through IV or injection—are typically much gentler and better tolerated.

Side Effects: Most people experience fewer or milder side effects with Niagen NR compared to direct NAD+ infusions. That makes NR a good option for those who are sensitive to NAD+ or want to support NAD+ levels with less discomfort.

Onset and Effectiveness: Niagen NR treatments work more gradually, as the body needs to convert NR into usable NAD+, but they offer powerful long-term support for energy, metabolism, and cellular repair.